The effect of flattening filter free delivery on endothelial dose enhancement with gold nanoparticles
نویسندگان
چکیده
منابع مشابه
The effect of flattening filter free delivery on endothelial dose enhancement with gold nanoparticles.
PURPOSE The aim of this study is to quantify and to compare the dose enhancement factor from gold nanoparticles (AuNP) to tumor endothelial cells for different concentrations of AuNP, and clinical MV beam configurations. METHODS Tumor endothelial cells are modeled as slabs measuring 10 × 10 × 2 μm. A spherical AuNP is simulated on the surface of the endothelial cell, within the blood vessel. ...
متن کاملEnhancement of the Dose on 12 MV Linac with Free Flattening Filter Mode
Purpose: In the last years, some studies investigated dosimetric benefits of a free flattening filter for the photon mode in the radiotherapy field. This study aims to provide a theoretical study published and analysis of basic dosimetric properties for a Saturne 43 Linac head to implement free flattening filter beams clinically. Material and Methods: Thi...
متن کاملEffect of dose rate on antitumor activity in hypoxic cells by using flattening filter free beams
Background: Recently, the Flattening Filter Free (FFF) beams, which allow a dose rate increase of up to four times compared to the normal dose rate, have been incorporated into radiation therapy machines. The aim of this study is to evaluate antitumor activity in hypoxic cells irradiated with different dose rates using FFF beams and to identify the casual mechanism for cellular damage during ir...
متن کاملGel dosimetry: The effect of gold nanoparticles on the dose enhancement in the external radiation therapy
Background: Normoxic type MAGICA gel dosimeters are established for dose quantification in three dimensions for radiotherapy. Objective(s): The ability of MAGICA polymer gel was assessed by experimental measurements method for studying the effect of gold nanoparticles (GNPs) in dose enhancement under the external 18MV radiotherapy practices. <...
متن کاملEffect of secondary electron generation on dose enhancement in Lipiodol with and without a flattening filter
PURPOSE Lipiodol, which was used in transcatheter arterial chemoembolization before liver stereotactic body radiation therapy (SBRT), remains in SBRT. Previous we reported the dose enhancement in Lipiodol using 10 MV (10×) FFF beam. In this study, we compared the dose enhancement in Lipiodol and evaluated the probability of electron generation (PEG) for the dose enhancement using flattening fil...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medical Physics
سال: 2013
ISSN: 0094-2405
DOI: 10.1118/1.4791671